My informant told me that a friend of hers used to say this phrase as sort of a superstitious prayer. It was sort of the opposite of the knock on wood superstition. The way it worked was that whenever my informant’s friend would talk about her kids, or her grandkids, by saying, “little Timmy’s so talented, he’s gonna be a fine doctor some day.”, or, “ That kid’s got a great arm, he’s gonna be a great ballplayer one day.”, immediately after she would say, “From my lips to God’s.”
There’s no getting around the fact that parents want the best for their kids, and I don’t doubt that there are a number of other similar types of sayings throughout the world. As I said before this saying is very similar to the knock on wood superstition, however instead of trying to ward off bad fortune, “From my lips to God’s ears” attempts to bring good fortune.